Hepatitis C

Hepatitis C is a contagious virus that can cause liver disease liver disease. it is sometimes called HCV for short.

Hepatitis means inflammation of the liver. When the liver’s inflamed (swollen and irritated), it has a harder time functioning properly. When this happens for a prolonged time, the liver starts to lose its ability to function, and a person may get sick.

Some people who get infected with hepatitis C never feel sick and recover completely. Others develop acute or chronic hepatitis C.

Risk Factors

Symptoms

The symptoms of hepatitis C are often mild. Most people carry the virus for years and don’t notice any symptoms. When they do notice symptoms, the most common ones are:

  • “brain fog” (the sense that you’re not thinking and concentrating normally)
  • fatigue
  • joint pain
  • loss of appetite
  • weight loss

Diagnosis

You don’t need a liver biopsy to determine if you have hepatitis C. Usually, two lab tests are used to diagnose it: hepatitis C antibody (Anti-HCV) and hepatitis C RNA (HCV RNA).

Hepatitis C Antibody (Anti-HCV)

This is the first hepatitis C test your healthcare providers will perform. It will find out if your body has antibodies against hepatitis C. A positive result means that at some point in your life, you were exposed to the hepatitis C virus, and you developed antibodies to it. But it doesn’t tell us if you’re still infected. So, if this test is positive, your healthcare providers will perform the hepatitis C RNA (HCV RNA) test to find out if you’re still infected.

Hepatitis C RNA (HCV RNA)

The hepatitis C RNA (HCV RNA) test will be used to find out if you still have the virus in your body. If the HCV RNA test is positive, you have chronic hepatitis C and should be considered for treatment to clear it.

Genotypes

Hepatitis C genotypes are different strains of the hepatitis C virus. There are six genotypes around the world. In Canada, the more common genotypes are 1, 2, and 3. Genotypes matter very little now, because the newer treatments are effective against all genotypes. In many jurisdictions, genotypes are no longer tested or reported.

Treatment

Since 2010, the medical community has made enormous progress in treating chronic hepatitis C. New medications called direct-acting antivirals (DAAs) act on the virus itself to rid it from the body. This is different than older medications like interferon, which works by stimulating an immune response.

These newer treatments are very effective and have cure rates of over 95%. Interferon is no longer used for hepatitis C treatment.

The newer treatments take less time (between 8 to 12 weeks), have fewer side effects, and appear to be effective at all stages of the disease.

Because these treatments are newer, they’re still expensive. But the cost is generally covered by provincial drug benefit programs or private insurance companies. Virtually all patients in Canada can now access these life-saving treatments that cure hepatitis C.

Alternative Therapies

If you’re trying alternative therapies such as herbal remedies, homeopathic medicines, and minerals, tell your healthcare providers. Please note: no alternative therapies have been proven safe and effective for clearing (curing) hepatitis C.

Q&A

References:

The information on this page was adapted (with permission) from the references below, by the Cirrhosis Care Alberta project team (physicians, nurse practitioners, registered nurses, registered dietitians, physiotherapists, pharmacists, and patient advisors).

This information is not intended to replace advice from your healthcare team. They know your medical situation best. Always follow your healthcare team’s advice.

References: 

  1. US Department of Veterans Affairs, Veterans Health Administration 
  2. Canadian Liver Foundation
Last reviewed March 15, 2021
Subscribe
Notify of
guest

We would really appreciate your feedback to make this page better. Thanks for taking the time to do this!

How would you best describe yourself?
I found this webpage useful
The content on this page is easy to navigate
I found what I was looking for on the page
0 Comments
Inline Feedbacks
View all comments